Anti-shock properties of the prostacyclin analog, iloprost, in traumatic shock.
RatHaemorrhage/shockUnspecifiedmale
Model: Noble-Collip drum traumatic shock under pentobarbital anaesthesia (35 mg/kg)
Iloprost prolonged survival time from 84 plus or minus 10 min to 243 plus or minus 36 min (p less than 0.01), reduced plasma myocardial depressant factor activity from 69 plus or minus 14 to 20 plus or minus 6 U/ml (p less than 0.01), and reduced plasma cathepsin D activity from 12 plus or minus 1.…
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