Trial title not recorded
Hypertension
Enrolment: 40 · Results not recorded
Loading the evidence…
Drug · Prostanoid IP receptor agonist (AGONIST); direct interaction, disease efficacy true
0 linked trials carry an injury-indication flag. These flags support record-level exploration and sit alongside the stringent aggregate counts described in Methods.
Hypertension
Enrolment: 40 · Results not recorded
Heart Failure With Normal Ejection Fraction
Enrolment: 34 · Results not recorded
Vaso-Occlusive Crises · Sickle Cell Disease
Enrolment: 144 · Results not recorded
Renal Insufficiency, Chronic · Coronary Angiography
Enrolment: 208 · Results not recorded
Mediastinal Mass
Enrolment: 60 · Results not recorded
Pulmonary Hypertension
Enrolment: 41 · Results not recorded
Pulmonary Arterial Hypertension
Enrolment: 797 · Results not recorded
2 studies reported at therapy level; 2 evidence entries itemised.
Model: Noble-Collip drum traumatic shock under pentobarbital anaesthesia (35 mg/kg)
Iloprost prolonged survival time from 84 plus or minus 10 min to 243 plus or minus 36 min (p less than 0.01), reduced plasma myocardial depressant factor activity from 69 plus or minus 14 to 20 plus or minus 6 U/ml (p less than 0.01), and reduced plasma cathepsin D activity from 12 plus or minus 1.…
Extraction: extract · Supplied extraction confidence: 0.75. Machine-extracted fields require source verification.
Model: Acute aortic ischaemia-reperfusion injury of the gastrocnemius muscle produced by clamping the abdominal aorta for 1 hour followed by 2 hours of reperfusion
Total oxidant status, creatine kinase and lactate dehydrogenase were highest in the untreated ischaemia-reperfusion group and lowest in controls; both iloprost and N-acetylcysteine groups had lower levels than untreated ischaemia-reperfusion and higher than controls (P < 0.05). Histopathology showe…
Extraction: extract · Subtype source: llm · Supplied extraction confidence: 0.75. Machine-extracted fields require source verification.