Evaluation of the effects of honey on acute-phase deep burn wounds.
MouseBurnContact / flameBALB/cCrSlcMalen = 126 mice across 4 groups, sampled at 30 minutes and on days…Topical, covered with gauze and wrapped with a sticky bandage0.2 mL of honey per wound; comparator 0.1 mL of 1 per cent…From day 0, the day of wounding
Model: Two circular deep burn wounds on each side of the shaved dorsum created with a 10 g weight heated in boiling water at 100 degrees Celsius applied for 20 seconds, under pentobarbital sodium anaesthesia (0.05 mg/g intraperitoneally)
Honey did not prevent burn wound progression, with no significant between-group difference in expanded wound area and no differences in any measure by day 4, although necrotic cell proportions and neutrophil numbers were lower with manuka and acacia honey than with silver sulfadiazine or no treatme…
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