THERAPY DOSSIER · th-ae5809b88e08

New Zealand manuka honey and Japanese acacia honey

Nutraceutical · Nutraceutical/medical-grade honey wound dressing; not a ChEMBL entity

Evidence & regulatory context

Mechanism: Nutraceutical/medical-grade honey wound dressing; not a ChEMBL entity
Target: Not recorded
Injury models: Burn
Reported indication: Not recorded
First approval: Not recorded
Development stage: Not recorded
ChEMBL record: Not recorded
ChEMBL max phase: Not recorded
Synonyms: Not recorded
Note: Not recorded

Clinical trials 2

0 linked trials carry an injury-indication flag. These flags support record-level exploration and sit alongside the stringent aggregate counts described in Methods.

NCT05605262 ↗PHASE2/PHASE3completed

100% Medical Grade Manuka Honey on Re-epithelialization Post Tympanoplasty

Tympanic Membrane Perforation

Enrolment: 64 · Results not recorded

NCT06873646 ↗EARLY_PHASE1not yet recruiting

Honey-Infused Alginate Wound Dressing (incl. Manuka honey dressing arm) for Diabetic Foot Ulcers

Diabetic Foot Ulcers

Enrolment: 110 · Results not recorded

Preclinical evidence 1

1 studies reported at therapy level; 1 evidence entries itemised.

PMID 24348720 ↗2013Mixed findings

Evaluation of the effects of honey on acute-phase deep burn wounds.

MouseBurnContact / flameBALB/cCrSlcMalen = 126 mice across 4 groups, sampled at 30 minutes and on days…Topical, covered with gauze and wrapped with a sticky bandage0.2 mL of honey per wound; comparator 0.1 mL of 1 per cent…From day 0, the day of wounding

Model: Two circular deep burn wounds on each side of the shaved dorsum created with a 10 g weight heated in boiling water at 100 degrees Celsius applied for 20 seconds, under pentobarbital sodium anaesthesia (0.05 mg/g intraperitoneally)

Honey did not prevent burn wound progression, with no significant between-group difference in expanded wound area and no differences in any measure by day 4, although necrotic cell proportions and neutrophil numbers were lower with manuka and acacia honey than with silver sulfadiazine or no treatme…

Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.9. Machine-extracted fields require source verification.

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