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PRECLINICAL PUBLICATION · 2013

Participation of autophagy in acute lung injury induced by seawater.

Rat / Other

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 24245991 ↗2013Reported benefit

Participation of autophagy in acute lung injury induced by seawater.

RatOtherSprague-DawleyMaleIntraperitonealBefore seawater exposure

Model: Seawater aspiration-induced acute lung injury

Seawater aspiration triggered autophagy; inhibition of autophagy with 3-MA partly ameliorated seawater-induced acute lung injury, with reduced lung weight coefficient, reduced TNF-alpha in bronchoalveolar lavage fluid and increased PaO2.

Extraction: extract · Supplied extraction confidence: 0.62. Machine-extracted fields require source verification.