Analysis of human embryonic stem cells with regulatable expression of the cell adhesion molecule L1 in regeneration after spinal cord injury
MouseSpinal cord injuryCompressionIntraspinal transplantation at three sites, the lesion, proximal and caudal
Model: Acute compression spinal cord injury in immunosuppressed mice
Mice transplanted with L1-on cells achieved better Basso Mouse Scale scores than those receiving L1-off cells, and at 6 weeks post-transplantation showed higher L1 expression, greater migration of transplanted cells and higher tyrosine hydroxylase immunoreactivity together with lower chondroitin su…
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