Functional electrical stimulation post-spinal cord injury improves locomotion and increases afferent input into the central nervous system in rats.
RatSpinal cord injuryUnspecifiedSprague-DawleyFemaleImplanted intramuscular stimulating electrodes in hindlimb musclesAcute phase after spinal cord injury, with assessment at day 7 post-injury
Model: Spinal cord injury in rats with chronic functional electrical stimulation electrodes implanted in hindlimb muscles
Functional electrical stimulation improved locomotor recovery at day 7 (BBB 10 plus or minus 2 versus 3 plus or minus 1 in controls, P less than 0.05) and significantly increased neurovascular activation in spinal cord and somatosensory cortex.
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