PebbleAtlas
PEBBLE / ATLAS
Open research access
PRECLINICAL PUBLICATION · 2013

Effect of black grape juice against heart damage from acute gamma TBI in rats.

Rat / Radiation

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 24084019 ↗2013Reported benefit

Effect of black grape juice against heart damage from acute gamma TBI in rats.

RatRadiationWistarMalen = 20 rats in total, 5 per group across four groupsOral gavage2 mL per animal per day; the methods also describe this as…One week before irradiation and continuing for 4 days after irradiation

Model: Single dose 6 Gy whole body gamma irradiation from a cobalt-60 source at 0.40 Gy per minute, source to skin distance 50 cm, under pentobarbital anaesthesia, producing acute radiation syndrome with heart damage

Irradiated rats given black grape juice had significantly lower serum lactate dehydrogenase from 24 h onwards and cardiac malondialdehyde maintained at basal levels compared with irradiated placebo rats.

Extraction: extract · Supplied extraction confidence: 0.9. Machine-extracted fields require source verification.