THERAPY DOSSIER · th-46f3024394c3

Organic black grape juice, resveratrol-rich, containing resveratrol 31.28 mg/L, quercetin 18.67 mg/L, caffeic acid 18.15 mg/L and total phenolics 223.14 mg/L

Nutraceutical

Evidence & regulatory context

Mechanism: Not recorded
Target: Not recorded
Injury models: Radiation
Reported indication: Not recorded
First approval: Not recorded
Development stage: Not recorded
ChEMBL record: Not recorded
ChEMBL max phase: Not recorded
Synonyms: Not recorded
Note: Not recorded

Clinical trials 2

0 linked trials carry an injury-indication flag. These flags support record-level exploration and sit alongside the stringent aggregate counts described in Methods.

NCT00455416 ↗PHASE2unknown

Dietary Intervention in Stage III/IV Follicular Lymphoma. Impact on Markers of Cell Proliferation, Apoptosis, Host Immune Cell Infiltrate and Oxidative Stress.

Follicular Lymphoma

Enrolment: 45 · Results not recorded

NCT04421079 ↗PHASE1completed

Clinical Pharmacology and Target Validation of A Bioactive Dietary Polyphenol Preparation (BDPP) For Stress-Related Disorders

Healthy Control

Enrolment: 84 · Results not recorded

Preclinical evidence 1

1 studies reported at therapy level; 1 evidence entries itemised.

PMID 24084019 ↗2013Reported benefit

Effect of black grape juice against heart damage from acute gamma TBI in rats.

RatRadiationWistarMalen = 20 rats in total, 5 per group across four groupsOral gavage2 mL per animal per day; the methods also describe this as…One week before irradiation and continuing for 4 days after irradiation

Model: Single dose 6 Gy whole body gamma irradiation from a cobalt-60 source at 0.40 Gy per minute, source to skin distance 50 cm, under pentobarbital anaesthesia, producing acute radiation syndrome with heart damage

Irradiated rats given black grape juice had significantly lower serum lactate dehydrogenase from 24 h onwards and cardiac malondialdehyde maintained at basal levels compared with irradiated placebo rats.

Extraction: extract · Supplied extraction confidence: 0.9. Machine-extracted fields require source verification.

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