Reversal of established traumatic brain injury-induced, anxiety-like behavior in rats after delayed, post-injury neuroimmune suppression.
RatTBIFluid percussionIntroduced 1 month after injury, with follow-up to 6 months after treatment
Model: Lateral fluid percussion traumatic brain injury in rats
Delayed anti-inflammatory treatment starting 1 month after lateral fluid percussion injury substantially reduced established freezing behaviour and reactive gliosis, with continued neuroprotective effects 6 months after treatment.
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