Caffeic acid phenethyl ester (CAPE) protects against acute urogenital injury following pneumoperitoneum in the rat.
RatIschaemia-reperfusionOther / unspecifiedWistar albinoMalen = 28 adult male rats in three groups with 7 animals per group…Not statedGiven in association with the laparoscopy and pneumoperitoneum protocol
Model: Ischaemia and reperfusion urogenital injury caused by 60 minutes of pneumoperitoneum at 15 mmHg, with tissues taken one hour before the desufflation period as described by the authors
Pneumoperitoneum raised total oxidant status and lowered total antioxidant status in kidney and testis and reduced the Johnsen score, and caffeic acid phenethyl ester prevented these changes, with no differences in prostate or in kidney and testis histology.
Extraction: extract · Supplied extraction confidence: 0.7. Machine-extracted fields require source verification.