Bi-layer composite dressing of gelatin nanofibrous mat and poly vinyl alcohol hydrogel for drug delivery and wound healing application: in-vitro and in-vivo studies.
RatWoundWistarMaleTopical application to the wound
Model: Full-thickness excision wound (acute wound model)
The epigallocatechin gallate-loaded bi-layer dressing increased wound contraction (from about 14% to 47%) and raised DNA (about 42%), total protein (about 32%), hydroxyproline (about 26%) and hexosamine (about 24%) with improved angiogenesis, re-epithelialisation and mature collagen deposition by d…
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