FRIEND: fibroids and unexplained infertility treated with epigallocatechin gallate
Uterine Leiomyoma
Enrolment: 33 · Results not recorded
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Nutraceutical
0 linked trials carry an injury-indication flag. These flags support record-level exploration and sit alongside the stringent aggregate counts described in Methods.
Uterine Leiomyoma
Enrolment: 33 · Results not recorded
Alzheimer's Disease
Enrolment: 21 · Results not recorded
Epidermolysis Bullosa Dystrophica
Enrolment: 18 · Results not recorded
Prostate Cancer
Enrolment: 5 · Results not recorded
Lung Cancer · Tobacco Use Disorder
Enrolment: 53 · Results not recorded
AL Amyloidosis · Cardiac Involvement
Enrolment: 38 · Results not recorded
Fragile X Syndrome
Enrolment: 44 · Results not recorded
Esophageal Cancer
Enrolment: 72 · Results not recorded
Breast Cancer
Enrolment: 1075 · Results not recorded
Relapsing-remitting Multiple Sclerosis
Enrolment: 120 · Results not recorded
Colon Cancer
Enrolment: 51 · Results not recorded
Unspecified Adult Solid Tumor
Enrolment not recorded · Results not recorded
Healthy
Enrolment: 40 · Results not recorded
Alzheimer Disease · Cognitive Decline
Enrolment: 129 · Results not recorded
Obesity
Enrolment: 15 · Results not recorded
Low-Grade Intraepithelial Neoplasia of Cervix
Enrolment: 50 · Results not recorded
Fetal Alcohol Syndrome
Enrolment: 36 · Results not recorded
4 studies reported at therapy level; 4 evidence entries itemised.
Model: Full-thickness excision wound (acute wound model)
The epigallocatechin gallate-loaded bi-layer dressing increased wound contraction (from about 14% to 47%) and raised DNA (about 42%), total protein (about 32%), hydroxyproline (about 26%) and hexosamine (about 24%) with improved angiogenesis, re-epithelialisation and mature collagen deposition by d…
Extraction: extract · Supplied extraction confidence: 0.68. Machine-extracted fields require source verification.
Model: Closed unilateral hip fracture by blunt guillotine impact: anaesthetised rats placed prone on a blunt guillotine ramming apparatus aimed at the proximal femur, with the guillotine lifted to 15 cm and released in free fall
EGCG pre-treatment significantly reduced the fracture-induced rise in serum mitochondrial DNA, lung injury score, lung wet to dry ratio, bronchoalveolar lavage total cell, monocyte/macrophage and neutrophil counts, and bronchoalveolar lavage TNF-alpha and IL-6 (all p less than 0.05).
Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.93. Machine-extracted fields require source verification.
Model: Experimental grade II corneal alkali burn
Topical epigallocatechin-3-gallate reduced corneal opacity, neovascularisation, oedema and inflammation and normalised epithelial morphology after alkali burn.
Extraction: extract · Supplied extraction confidence: 0.7. Machine-extracted fields require source verification.
Model: Moderate thoracic contusion spinal cord injury using the MASCIS impactor
Intravenous EGCG infused for 36 h improved locomotor and sensory recovery and pain thresholds in both acute and one-year chronic injured rats, and reduced lesion size and increased neuronal numbers in the acute group.
Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.75. Machine-extracted fields require source verification.