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PRECLINICAL PUBLICATION · 2013

Effect of preconditioning with hyperbaric oxygen on neural cell apoptosis after spinal cord injury in rats.

Rat / Spinal cord injury

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 23877270 ↗2013Reported benefit

Effect of preconditioning with hyperbaric oxygen on neural cell apoptosis after spinal cord injury in rats.

RatSpinal cord injuryContusionSprague-Dawleyfemalen = 55 rats in total: hyperbaric oxygen preconditioning n = 25,…hyperbaric chamber exposurebefore injury (preconditioning)

Model: Acute spinal cord injury induced by the Allen weight-drop method

Hyperbaric oxygen preconditioning reduced the number of TUNEL-positive apoptotic cells and improved neurological recovery compared with the normal injury and control groups, with statistically significant differences between groups.

Extraction: extract · Subtype source: llm · Supplied extraction confidence: 0.7. Machine-extracted fields require source verification.