Impact of beta-1,3-glucan isolated from Euglena gracilis on corneal epithelial cell migration and on wound healing in a rat alkali burn model.
RatBurnChemical / corrosiveSprague-DawleyMalen = n=10 eyes per group in four groups, total 40 eyes of 40 ratsTopical ocular200 microgram/ml topically; 50, 100 and 200 microgram/ml in…After alkali injury
Model: Corneal alkali burn induced with 1 N sodium hydroxide in 40 eyes of 40 rats
The wound healing ratio was greatest with hyaluronic acid conjugated beta-1,3-glucan at 96.0 plus or minus 4.1 per cent, followed by beta-1,3-glucan at 86.0 plus or minus 6.5 per cent, laminarin at 67.0 plus or minus 7.5 per cent and injury only at 54.0 plus or minus 6.5 per cent. Opacity scores fo…
Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.8. Machine-extracted fields require source verification.