THERAPY DOSSIER · th-6a529b9ded1f

Beta-1,3-glucan from Euglena gracilis, alone and conjugated with hyaluronic acid, compared with laminarin

Nutraceutical

Evidence & regulatory context

Mechanism: Not recorded
Target: Not recorded
Injury models: Burn
Reported indication: Not recorded
First approval: Not recorded
Development stage: Not recorded
ChEMBL record: Not recorded
ChEMBL max phase: Not recorded
Synonyms: Not recorded
Note: Not recorded

Clinical trials 2

0 linked trials carry an injury-indication flag. These flags support record-level exploration and sit alongside the stringent aggregate counts described in Methods.

NCT05431751 ↗NAunknown

Clinical proof-of-concept study on immune surveillance and alertness (Whole Algae, Euglena-derived beta-glucan)

Immune Surveillance

Enrolment: 24 · Results not recorded

NCT03769012 ↗NAcompleted

Beta-glucan to augment immune function and decrease URTI incidence in marathon runners

Cold · Flu · Stress · Gastrointestinal Tolerance

Enrolment: 60 · Results not recorded

Preclinical evidence 1

1 studies reported at therapy level; 1 evidence entries itemised.

PMID 23841526 ↗2013Reported benefit

Impact of beta-1,3-glucan isolated from Euglena gracilis on corneal epithelial cell migration and on wound healing in a rat alkali burn model.

RatBurnChemical / corrosiveSprague-DawleyMalen = n=10 eyes per group in four groups, total 40 eyes of 40 ratsTopical ocular200 microgram/ml topically; 50, 100 and 200 microgram/ml in…After alkali injury

Model: Corneal alkali burn induced with 1 N sodium hydroxide in 40 eyes of 40 rats

The wound healing ratio was greatest with hyaluronic acid conjugated beta-1,3-glucan at 96.0 plus or minus 4.1 per cent, followed by beta-1,3-glucan at 86.0 plus or minus 6.5 per cent, laminarin at 67.0 plus or minus 7.5 per cent and injury only at 54.0 plus or minus 6.5 per cent. Opacity scores fo…

Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.8. Machine-extracted fields require source verification.

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