Antioxidant, hepatoprotective and hypolipidemic effects of methanolic root extract of Cassia singueana in rats following acute and chronic carbon tetrachloride intoxication.
RatChemical/toxinWistarMaleIntraperitoneal5 mg/kgPretreatment before carbon tetrachloride intoxication in the acute study, and t…
Model: Acute and chronic carbon tetrachloride intoxication causing hepatic and oxidative injury
Extract treatment significantly reduced malondialdehyde in liver, kidney and heart (for example liver 0.18 to 0.15 nmol/mg), lowered serum aspartate aminotransferase, alanine aminotransferase, bilirubin and total cholesterol, and raised HDL cholesterol, superoxide dismutase and catalase relative to…
Extraction: extract · Supplied extraction confidence: 0.6. Machine-extracted fields require source verification.