Microglial activation induced by traumatic brain injury is suppressed by postinjury treatment with hyperbaric oxygen therapy.
RatTBIFluid percussionSprague-DawleyMaleHyperbaric chamber100% oxygen at 2.0 absolute atmospheres1 h after injury (HBO I) or 8 h after injury (HBO II)
Model: Fluid percussion traumatic brain injury
Hyperbaric oxygen at either 1 or 8 h after injury improved inclined plane performance and reduced infarction, microglial activation, TNF-alpha expression and neuronal apoptosis.
Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.7. Machine-extracted fields require source verification.