Human astrocytes derived from glial restricted progenitors support regeneration of the injured spinal cord.
RatSpinal cord injuryHemisection / partialAthymic nude ratTransplantation into the lesion siteAcute transplantation at the time of lesion
Model: Cervical dorsal column lesion
Both human glial restricted progenitors and derived astrocytes survived and promoted regeneration of ascending sensory axons into the lesion, with no differences between differentiation protocols, and cells from frozen stocks behaved similarly.
Extraction: extract · Subtype source: llm · Supplied extraction confidence: 0.65. Machine-extracted fields require source verification.