Topical tacrolimus does not negatively impact acute skin wound healing.
MouseWoundHairless micen = 45 mice with two wounds each; 10 wounds per group at each t…TopicalApplied after wounding
Model: Two full-thickness excisional skin wounds on the back
Tacrolimus-treated wounds showed healing patterns similar to vehicle, with slightly decreased IL-1 alpha and TGF-beta mRNA, whereas clobetasol propionate delayed re-epithelialisation and leucocyte infiltration.
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