PRECLINICAL PUBLICATION · 2013

Effect of infliximab combined with methylprednisolone on expressions of NF-kB, TRADD, and FADD in rat acute spinal cord injury.

Rat / Spinal cord injury

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

Infliximab

PMID 23574812 ↗2013Reported benefit

Effect of infliximab combined with methylprednisolone on expressions of NF-kB, TRADD, and FADD in rat acute spinal cord injury.

RatSpinal cord injuryUnspecifiedSprague-DawleyMalen = 180 rats (10 rats x 6 groups for each of three assessments)After acute spinal cord injury

Model: Acute spinal cord injury

Both agents lowered NF-kB, TRADD and FADD at 24 hours and raised BBB scores at 14 and 21 days, with the combination producing the greatest improvement.

Extraction: extract · Supplied extraction confidence: 0.7. Machine-extracted fields require source verification.