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PRECLINICAL PUBLICATION · 2013

The neuroprotective mechanism of puerarin treatment of acute spinal cord injury in rats.

Rat / Ischaemia-reperfusion

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 23570727 ↗2013Reported benefit

The neuroprotective mechanism of puerarin treatment of acute spinal cord injury in rats.

RatIschaemia-reperfusionSpinalSprague-DawleyMaleIntraperitoneal50 mg/kgFirst injections at 1, 2, 4 and 6 hours after reperfusion

Model: Acute spinal cord ischaemia-reperfusion injury

Puerarin improved motor deficit and lowered glutamate levels and mGluR-1 mRNA expression after spinal cord ischaemia-reperfusion injury.

Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.8. Machine-extracted fields require source verification.