Effects of antidepressant and treadmill gait training on recovery from spinal cord injury in rats.
RatSpinal cord injuryUnspecifiedWistarn = 48 rats in four groupsIntraperitonealFluoxetine 0.3 ml per 100 g body weightFluoxetine beginning 24 hours after the trauma
Model: Standardised acute spinal cord injury
The combination of fluoxetine and treadmill gait training gave significantly greater BBB improvement than either therapy alone from day 14 to day 42, and all treated groups had better motor-evoked potentials than controls.
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