Amelioration of dextran sulphate sodium-induced colitis in mice by echinacoside-enriched extract of Cistanche tubulosa.
MouseChemical/toxinC3HMalen = n = 8 per groupOral
Model: Dextran sulphate sodium (DSS)-induced acute colitis
Oral echinacoside-enriched extract significantly lowered disease activity index and prevented colonic damage, protecting the intestinal epithelium, with upregulated TGF-beta1 and increased Ki67-positive proliferating cells. The effect on inflammatory cellular infiltration was not significant.
Extraction: extract · Supplied extraction confidence: 0.7. Machine-extracted fields require source verification.