Transcorneal alternating current stimulation after severe axon damage in rats results in long-term silent survivor neurons.
RatCrushPeripheral-nerve crushMaleTranscorneal electrical stimulation under anaesthesiaFirst treatment immediately after the lesion
Model: Severe optic nerve crush
On day 28 after crush, tACS-treated rats showed 28.2 percent neuronal survival compared with 8.6 percent in sham operates, indicating long-term protection from delayed retrograde cell death. All crush animals nevertheless remained impaired in brightness discrimination regardless of treatment and th…
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