The effect of subcutaneous mesenchymal stem cell injection on statis zone and apoptosis in an experimental burn model.
RatBurnContact / flameSprague-DawleyMalen = Cell donors n = 10; treated n = 10; saline control n = 10;…Subcutaneous injection into the stasis zone30 minutes after the burn injury
Model: Thermal comb burn model on the back, assessing the zone of stasis
Apoptosis counts were significantly lower and the scintigraphic percentage of vital tissue in the stasis zone significantly higher in mesenchymal stem cell-treated rats than in saline controls. Systemic cytokine levels did not differ significantly between the groups.
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