Blue light eliminates community-acquired methicillin-resistant Staphylococcus aureus in infected mouse skin abrasions.
MouseWoundBALB/cFemaleTopical illumination of the infected abrasion41.4 J/cm2 on day 0 and 108 J/cm2 on day 1 in vivo; 170 J/c…30 min after bacterial inoculation for acute infection and 24 h after inoculati…
Model: Skin abrasion inoculated with bioluminescent community-acquired MRSA strain USA300LAC::lux
Blue light produced more than a 2-log10 reduction in bacterial luminescence in mouse skin abrasions in both acute and established infections while sparing keratinocytes, although bacterial regrowth occurred by 24 h after therapy.
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