Protective effect of ginkgolide B against acute spinal cord injury in rats and its correlation with the Jak/STAT signaling pathway.
RatSpinal cord injuryContusionSprague-DawleyMaleAfter injury; exact interval not stated
Model: Acute T10 spinal cord injury by the modified Allen weight-drop method
Ginkgolide B improved inclined plane and locomotor scores from day 3 to day 14, comparably with methylprednisolone, and inhibited JAK2 and STAT3 phosphorylation, raised the Bcl-2 to Bax ratio, lowered caspase-3 and reduced the apoptosis index.
Extraction: extract · Subtype source: llm · Supplied extraction confidence: 0.6. Machine-extracted fields require source verification.