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PRECLINICAL PUBLICATION · 2013

Hydrogen protects rats from dermatitis caused by local radiation.

Rat / Radiation

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 23273331 ↗2013Mixed findings

Hydrogen protects rats from dermatitis caused by local radiation.

RatRadiationSprague-DawleyMaleSubcutaneous injectionBefore irradiation

Model: Local single-dose or fractionated irradiation of the head and neck area (single 15, 20 or 25 Gy, or a cumulative 30 Gy in three fractions)

Hydrogen reduced dermatitis severity, accelerated tissue recovery and limited weight loss after single doses of 15 or 20 Gy and after 30 Gy in three fractions, but not after a single 25 Gy dose, and protected HaCaT cells in vitro.

Extraction: extract · Supplied extraction confidence: 0.6. Machine-extracted fields require source verification.