The effect of methylprednisolone intravenous infusion on the expression of ciliary neurotrophic factor in a rat spinal cord injury model.
RatSpinal cord injuryUnspecifiedLong-Evansn = 30 rats randomised into two groupsIntravenous infusion
Model: Standardised experimental spinal cord injury
Mean ciliary neurotrophic factor expression was lower in the methylprednisolone group at 12 h (p = 0.006) and 24 h (p = 0.008) after injury than in the saline control group, with no significant difference at 6, 48 or 72 h. No functional outcome was reported.
Extraction: extract · Supplied extraction confidence: 0.75. Machine-extracted fields require source verification.