Blue light rescues mice from potentially fatal Pseudomonas aeruginosa burn infection: efficacy, safety, and mechanism of action.
MouseBurnUnspecifiedBALB/cFemaleTopical illumination of the infected burn55.8 J/cm230 min after bacterial inoculation
Model: Burn wound inoculated with Pseudomonas aeruginosa
A single blue light exposure reduced the area under the bioluminescence time curve approximately 100-fold compared with untreated infected burns (p < 0.0001) and increased survival from 18.2% to 100% (p < 0.0001), with no significant histological skin damage at the effective dose.
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