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PRECLINICAL PUBLICATION · 2012

Protective effect of anthocyanins from lingonberry on radiation-induced damages.

Mouse / Radiation

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 23249859 ↗2012Reported benefit

Protective effect of anthocyanins from lingonberry on radiation-induced damages.

MouseRadiationKunmingMale and femalen = 60 mice in total, 10 per group across six groupsIntragastric50, 100 and 200 mg/kg body weight per dayPre-treatment beginning 14 days before irradiation, with irradiation on day 15

Model: Whole-body 60Co gamma irradiation at 6.0 Gy, dose rate 1.01 Gy/min, source to animal distance 160 cm

Pre-treatment with lingonberry anthocyanins raised irradiation-depressed white blood cell, red blood cell, haemoglobin and platelet counts (p < 0.01), increased spleen indices at all doses and thymus indices at 100 and 200 mg/kg, increased splenocyte proliferation dose dependently, and reduced bone…

Extraction: extract · Supplied extraction confidence: 0.9. Machine-extracted fields require source verification.