THERAPY DOSSIER · th-c861e6f3a3cf

Anthocyanins from lingonberry (Vaccinium vitis-idaea)

Nutraceutical · Botanical (lingonberry anthocyanins); not a discrete ChEMBL entity

Evidence & regulatory context

Mechanism: Botanical (lingonberry anthocyanins); not a discrete ChEMBL entity
Target: Not recorded
Injury models: Radiation
Reported indication: Not recorded
First approval: Not recorded
Development stage: Not recorded
ChEMBL record: Not recorded
ChEMBL max phase: Not recorded
Synonyms: Not recorded
Note: Not recorded

Clinical trials 1

0 linked trials carry an injury-indication flag. These flags support record-level exploration and sit alongside the stringent aggregate counts described in Methods.

NCT07381933 ↗NArecruiting

The Effect of Consumed Berries (incl. Lingonberries) on Extracellular Vesicle Signalling

Healthy

Enrolment: 60 · Results not recorded

Preclinical evidence 1

1 studies reported at therapy level; 1 evidence entries itemised.

PMID 23249859 ↗2012Reported benefit

Protective effect of anthocyanins from lingonberry on radiation-induced damages.

MouseRadiationKunmingMale and femalen = 60 mice in total, 10 per group across six groupsIntragastric50, 100 and 200 mg/kg body weight per dayPre-treatment beginning 14 days before irradiation, with irradiation on day 15

Model: Whole-body 60Co gamma irradiation at 6.0 Gy, dose rate 1.01 Gy/min, source to animal distance 160 cm

Pre-treatment with lingonberry anthocyanins raised irradiation-depressed white blood cell, red blood cell, haemoglobin and platelet counts (p < 0.01), increased spleen indices at all doses and thymus indices at 100 and 200 mg/kg, increased splenocyte proliferation dose dependently, and reduced bone…

Extraction: extract · Supplied extraction confidence: 0.9. Machine-extracted fields require source verification.

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