Effects of resveratrol on incisional wound healing in rats.
RatWoundWistar-AlbinoFemalen = 10 animals per group sacrificed on each of postoperative da…Oral0.5 mg/kgStarted 7 days before the operation until 12 h before surgery, then maintained…
Model: 4 cm midline laparotomy incision
Resveratrol significantly increased fascial tensile strength and hydroxyproline levels at day 14 and raised acute inflammation, collagen deposition and neovascularisation scores at days 7 and 14, with higher granulation tissue and fibroblast maturation scores at day 14.
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