Differential effects of activity dependent treatments on axonal regeneration and neuropathic pain after peripheral nerve injury.
RatOtherSprague-DawleyFemaleElectrical stimulation applied to the injured nerve and whole-body forced treadmill exerciseElectrical stimulation for 4 hours after injury; forced treadmill running for 5…
Model: Sciatic nerve section with immediate suture repair
Sciatic nerve section induced hyperalgesia in the medial plantar skin of the injured paw, which both treadmill running and electrical stimulation reduced by different routes. Electrical stimulation enhanced motor and sensory reinnervation, and combining it with treadmill running produced strong ago…
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