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PRECLINICAL PUBLICATION · 2012

Implications of olfactory lamina propria transplantation on hyperreflexia and myelinated fiber regeneration in rats with complete spinal cord transection.

Rat / Spinal cord injury

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 23179588 ↗2012No effect reported

Implications of olfactory lamina propria transplantation on hyperreflexia and myelinated fiber regeneration in rats with complete spinal cord transection.

RatSpinal cord injuryComplete transectionSprague-DawleyMaleTransplantation into the spinal cord lesion siteAcute, 2 week delayed and 4 week delayed transplantation

Model: Complete spinal cord transection in adult rats

Neither olfactory nor respiratory lamina propria grafts produced considerable improvement in withdrawal reflex responses or in low-frequency dependent depression of the H-reflex, and the two graft types gave comparable myelinated fibre density and estimated total fibre number at the lesion site. An…

Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.6. Machine-extracted fields require source verification.