Hydrogen rich saline reduces immune-mediated brain injury in rats with acute carbon monoxide poisoning.
RatChemical/toxinSprague-DawleymaleGiven after carbon monoxide poisoning
Model: Acute carbon monoxide poisoning causing brain injury in rats
Hydrogen-rich saline given after carbon monoxide poisoning reduced neuron loss, restored antioxidant capacity, normalised myelin basic protein recognition and lowered macrophage aggregation and MIP-1-alpha and ICAM-1 expression.
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