Metalloproteinases and their associated genes contribute to the functional integrity and noise-induced damage in the cochlear sensory epithelium.

Metalloproteinases and their associated genes contribute to the functional integrity and noise-induced damage in the cochlear sensory epithelium.

Model: Noise induced cochlear injury from acoustic overstimulation

Short term doxycycline reduced hearing loss and sensory cell death, whereas 7 day treatment worsened hearing sensitivity and potentiated noise induced hearing loss.

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