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PRECLINICAL PUBLICATION · 2012

The neuroprotective effect of acute moderate alcohol consumption on caspase-3 mediated neuroapoptosis in traumatic brain injury: the role of lysosomal cathepsin L and nitric oxide.

Rat / TBI

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 23099040 ↗2012Reported benefit

The neuroprotective effect of acute moderate alcohol consumption on caspase-3 mediated neuroapoptosis in traumatic brain injury: the role of lysosomal cathepsin L and nitric oxide.

RatTBIUnspecifiedSprague-DawleyMalen = 29 rats across four groups

Model: Experimental traumatic brain injury after craniotomy

Caspase-3 activity rose after trauma and was lower in the trauma plus alcohol group, suggesting reduced apoptotic cell death.

Extraction: extract · Supplied extraction confidence: 0.6. Machine-extracted fields require source verification.