Effect of hormone replacement therapy in matrix metalloproteinase expression and intimal hyperplasia development after vascular injury.
RatOtherSprague-DawleyFemaleSubcutaneous slow release pelletStarted 4 weeks after ovariectomy, 6 weeks before balloon angioplasty
Model: Balloon angioplasty injury of the left common carotid artery in ovariectomised aged rats
Hormone therapy raised intima to media ratio versus placebo without reaching significance and increased MMP-2 and MMP-9 without a compensatory rise in TIMP-2.
Extraction: extract · Supplied extraction confidence: 0.7. Machine-extracted fields require source verification.