PebbleAtlas
PEBBLE / ATLAS
Open research access
PRECLINICAL PUBLICATION · 2012

Direct isolation and RNA-seq reveal environment-dependent properties of engrafted neural stem/progenitor cells.

Mouse / Spinal cord injury

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 23072808 ↗2012Reported benefit

Direct isolation and RNA-seq reveal environment-dependent properties of engrafted neural stem/progenitor cells.

MouseSpinal cord injuryUnspecifiedAcute transplantation after injury

Model: Spinal cord injury with acute transplantation of neural stem/progenitor cells

Acutely transplanted cells were beneficial through neuroprotection and secretion, but transcription, signalling and neural differentiation were suppressed in the injured environment.

Extraction: extract · Supplied extraction confidence: 0.6. Machine-extracted fields require source verification.