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PRECLINICAL PUBLICATION · 2012

Mesenchymal stem cell transplantation reduces glial cyst and improves functional outcome after spinal cord compression.

Mouse / Spinal cord injury

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 23022648 ↗2012Reported benefit

Mesenchymal stem cell transplantation reduces glial cyst and improves functional outcome after spinal cord compression.

MouseSpinal cord injuryCompressionC57BL/6MaleTransplantation into the lesion cavityAcutely after injury

Model: Spinal cord compression injury

Acute transplantation of mesenchymal stem cells into the compressed spinal cord reduced lesion volume by 31.6 per cent and improved posture, hindlimb flexion, sensory and foot-fault scores compared with untreated injured mice, for example 7.50 versus 15.83 foot-fault mistakes.

Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.65. Machine-extracted fields require source verification.