Potential of sivelestat in protection against severe acute pancreatitis-associated lung injury in rats.
RatChemical/toxinSprague-DawleyMaleIntravenous
Model: Severe acute pancreatitis induced by intraductal infusion of 5% sodium taurocholate, with secondary acute lung injury
Intravenous sivelestat attenuated taurocholate-induced abnormalities in all measured circulatory, pulmonary and pancreatic parameters except serum amylase concentration.
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