PebbleAtlas
PEBBLE / ATLAS
Open research access
PRECLINICAL PUBLICATION · 2012

Amelioration of radiation-induced acute inflammation and mucosal atrophy by beta-hydroxy-beta-methylbutyrate, L-glutamine, and L-arginine: results of an experimental study.

Rat / Radiation

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 22993027 ↗2012Reported benefit

Amelioration of radiation-induced acute inflammation and mucosal atrophy by beta-hydroxy-beta-methylbutyrate, L-glutamine, and L-arginine: results of an experimental study.

RatRadiationWistarFemalen = 28 rats in four groupsOral5.2 g HMB, 29.6 g arginine and 29.6 g glutamine scaled from…Started on the day of radiotherapy

Model: Single 17 Gy radiation dose to the head and neck area causing acute oral mucositis

HMB/Glu/Arg reversed radiation-induced epithelial atrophy (p 0.006) and significantly reduced radiation-induced inflammation (p 0.007).

Extraction: extract · Supplied extraction confidence: 0.75. Machine-extracted fields require source verification.