PRECLINICAL PUBLICATION · 2012

Effects of low-level laser therapy (LLLT) and diclofenac (topical and intramuscular) as single and combined therapy in experimental model of controlled muscle strain in rats.

Rat / Other

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

Low-level laser therapy (810 nm) compared with topical and intramuscular diclofenac

PMID 22989160 ↗2012Reported benefit

Effects of low-level laser therapy (LLLT) and diclofenac (topical and intramuscular) as single and combined therapy in experimental model of controlled muscle strain in rats.

RatOtherWistarMaleTranscutaneous laser irradiation3 J, 810 nm, 100 mW1 h after injury

Model: Controlled muscle strain induced by overloading the tibialis anterior muscle

All treatments reduced COX-1 and COX-2 expression versus injury (p<0.05), and laser therapy outperformed topical and intramuscular diclofenac for prostaglandin E2 and walking track outcomes (p<0.05).

Extraction: extract · Supplied extraction confidence: 0.7. Machine-extracted fields require source verification.