THERAPY DOSSIER · th-33f616d595fa

Low-level laser therapy (810 nm) compared with topical and intramuscular diclofenac

Device

Evidence & regulatory context

Mechanism: Not recorded
Target: Not recorded
Injury models: Other
Reported indication: Not recorded
First approval: Not recorded
Development stage: Not recorded
ChEMBL record: Not recorded
ChEMBL max phase: Not recorded
Synonyms: Not recorded
Note: Not recorded

Clinical trials 6

1 linked trials carry an injury-indication flag. These flags support record-level exploration and sit alongside the stringent aggregate counts described in Methods.

NCT06370910 ↗Injury indicationNAcompleted

Comparison of Low-Level Laser Therapy With Cryotherapy in Postpartum Women With Laceration and/or Episiotomy

Episiotomy; Complications · Laceration

Enrolment: 56 · Results not recorded

NCT05413993 ↗NAcompleted

Immediate Effect Of Photobiomodulation On Ph And Salivary Flow: Quasi-Experimental Clinical Trial

Xerostomia

Enrolment: 20 · Results not recorded

NCT02118155 ↗NAcompleted

Connective Tissue Graft Associated or Not With Low Intensity Laser Therapy: A Randomized Clinical Trial

Gingival Recession

Enrolment: 40 · Results not recorded

NCT06808178 ↗NAcompleted

The Effect of Kinesio Taping and Low Level Laser Therapy in Patient With Post Mastectomy Related Lymphedema

Lymphedema · Breast Cancer Stage II

Enrolment: 90 · Results not recorded

NCT05753540 ↗NAcompleted

Effects of MLS LASER Therapy in Patients With Chronic Nonspecific Neck Pain: Randomized Controlled Trial Versus Placebo

Chronic Non-specific Neck Pain

Enrolment: 47 · Results not recorded

NCT05265416 ↗NAcompleted

Comparison Between the Effect of Piezocision and Low-level Laser Therapy on Patient-centered Outcomes in Upper Canine Retraction

Class II Malocclusion

Enrolment: 58 · Results not recorded

Preclinical evidence 1

1 studies reported at therapy level; 1 evidence entries itemised.

PMID 22989160 ↗2012Reported benefit

Effects of low-level laser therapy (LLLT) and diclofenac (topical and intramuscular) as single and combined therapy in experimental model of controlled muscle strain in rats.

RatOtherWistarMaleTranscutaneous laser irradiation3 J, 810 nm, 100 mW1 h after injury

Model: Controlled muscle strain induced by overloading the tibialis anterior muscle

All treatments reduced COX-1 and COX-2 expression versus injury (p<0.05), and laser therapy outperformed topical and intramuscular diclofenac for prostaglandin E2 and walking track outcomes (p<0.05).

Extraction: extract · Supplied extraction confidence: 0.7. Machine-extracted fields require source verification.

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