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PRECLINICAL PUBLICATION · 2012

The effect of curcumin on lung injuries in a rat model induced by aspirating gastrointestinal decontamination agents.

Rat / Chemical/toxin

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 22974604 ↗2012Reported benefit

The effect of curcumin on lung injuries in a rat model induced by aspirating gastrointestinal decontamination agents.

RatChemical/toxinSprague-DawleyFemalen = n=7 per group in 6 groupsIntraperitoneal150 mg/kgAfter aspiration

Model: Aspiration of polyethylene glycol solution or activated charcoal causing acute lung injury

Curcumin attenuated pulmonary inflammation and alveolar damage, lowered serum malondialdehyde and surfactant protein D, and inhibited TNF-alpha and IL-1beta expression.

Extraction: extract · Supplied extraction confidence: 0.7. Machine-extracted fields require source verification.