Midbrain raphe stimulation improves behavioral and anatomical recovery from fluid-percussion brain injury.
RatTBIFluid percussionImplanted intracerebral stimulating electrodeIntermittent 8 Hz pulse trains, with a higher frequency 24…Beginning 4 to 6 h after injury, with a delayed-start protocol beginning 7 days…
Model: Moderate parasagittal (right) fluid percussion traumatic brain injury
Early 8 Hz median and dorsal raphe stimulation restored reference memory acquisition and reduced cortical volume loss, early 8 Hz median raphe stimulation also restored spatial working memory, all protocols reversed forelimb reaching asymmetry, and 8 Hz median raphe stimulation reversed injury-indu…
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