BDNF expression with functional improvement in transected spinal cord treated with neural stem cells in adult rats.
RatSpinal cord injuryComplete transectionSprague-DawleyLocal graft into the injury siteAcute stage after injury
Model: Spinal cord transection
Neural stem cell grafts significantly improved sensory and locomotor function and increased BDNF protein and mRNA at the injury site, with somatosensory evoked potentials recorded in grafted rats despite little corticospinal tract regeneration.
Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.6. Machine-extracted fields require source verification.