Regeneration of mature dermis by transplanted particulate acellular dermal matrix in a rat model of skin defect wound.
RatWoundSprague-DawleyMalen = 12 male recipient rats, experimental group n = 6 and contro…Implantation into the full-thickness skin defect, covered with vaseline gauze and povidone-iodine gauzeAt the time of wounding
Model: Acute full-thickness dorsal skin defect of original area 4 x 6 cm
Allogeneic particulate acellular dermal matrix used as a dermal regeneration template facilitated maturation and improved collagen bundle structure of the regenerated dermis at 20 weeks after surgery. The preparation method produced particles with a narrower size distribution than previously report…
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